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Carson Wentz will see his first action since being shelved 10 months ago and last season’s top two rushers were cut from the final 53-man roster, so Philly has some question marks. Washington will ride with Case Keenum, who was initially signed to be the backup QB and is being pressed into duty because Colt McCoy’s return from a broken fibula hit a snag. Scoring won’t come easily since a no-name group of receivers will have issues getting open and top tackle Trent Williams remains a holdout, which means protection should be a problem.
Matt Blunt (VegasInsider - NFL)
NFL - Derrick Henry - Over 87 Rush Yards
Tennessee starts the year in Cleveland and is the first team to get a crack at tearing down the Cleveland hype train that has been gaining steam all summer long. The best way to do that is to feed their stud RB Henry and allow him to churn yards to keep that Browns attack sitting on the sidelines. Tennessee will need a big day from Henry to pull off the win and they should get the former in that scenario for sure.
The 49ers were the only team in the NFL not to win a road game last season by going 0-8 on the highway, which included a loss at Tampa Bay. San Francisco looks to break through on the road with a cross-country trip to Tampa Bay. The Bucs are led by new head coach Bruce Arians after a short retirement from Arizona, as Tampa Bay posted a 1-3 ATS record last season in the role of a home favorite. San Francisco has not gotten off to good starts the last two seasons under Kyle Shanahan, but also got three games from Jimmy Garoppolo before he tore his ACL. I'll back the 49ers here as a short underdog.
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